KleineLevin syndrome (KLS) is a rare disease characterized by recurrent episodes of hypersomnia and to various degrees, behavioral or cognitive disturbances, compulsive eating behavior, and hypersexuality. [1] The disease predominantly affects adolescent males.
What are the symptoms of Kleine Levin Syndrome?
Symptoms occur as episodes, typically lasting a few days to a few weeks. Episode onset is often abrupt, and may be associated with flu-like symptoms. Excessive food intake, irritability, childishness, disorientation, hallucinations, and an abnormally uninhibited sex drive may be observed during episodes.
What is Kevin Levin Syndrome?
Kleine Levin syndrome is a rare disorder characterized by recurrent episodes of excessive sleep (hypersomnia) along with cognitive and behavioral changes. Affected individuals may sleep for up to 20 hours per day during an episode.
How is KLS similar to narcolepsy?
In contrast to narcolepsy, KLS is a relapsing disorder with mean duration of 14 years. In addition to excessive sleepiness, the KLS patients also have cognitive (working memory, language), perceptual (delusions, hallucinations), and behavioral disturbances (binge eating, hypersexuality) during their sleep episodes.
How is KLS treated?
Stimulant pills are an option for treating KLS. Although they can cause irritability, these medications promote wakefulness and are effective at reducing sleepiness. Options include methylphenidate (Concerta) and modafinil (Provigil). Medications that treat mood disorders may also be beneficial.
How many people are affected by Kleine-Levin Syndrome?
It affects around 1/500 000 individuals. Patients are mostly male (68-78% of cases) and adolescents (81% of patients), with a mean age of onset of 15 years (range 4-82 years).
What causes Kleine-Levin?
The exact cause of Kleine-Levin syndrome is unknown. It is speculated that symptoms may develop due to malfunction or damage to the portion of the brain that helps to regulate functions such as sleep, appetite, and body temperature (hypothalamus).
How long do KLS episodes last?
The median duration of KLS episodes is about ten days, but some last several weeks or months. A study of 108 patients found an average of 19 episodes over the duration of the disease.
What are the 5 major sleep disorders?
5 Major Sleep Disorders
- Restless Legs Syndrome (RLS) RLS is a condition that causes your legs to move or shake because of an unpleasant sensation. …
- Insomnia. …
- REM Sleep Behavior Disorder (RBD) …
- Sleep Apnea. …
- Narcolepsy.
What is the rarest sleep disorder?
Kleine-Levin Syndrome (KLS), also known as Sleeping Beauty syndrome, is a rare neurological disorder characterised by recurrent bouts of hypersomnolence (excessive sleeping) along with cognitive and behavioural problems during wakefulness.
What is Klein’s disease?
Klein’s Syndrome, also known as Waardenburg Syndrome, is a rare genetic disorder that is characterized by deafness, defects in structures arising from the neural crest, nose deformities and skin, iris and hair pigmentation abnormalities.
How is KLS diagnosed?
To be diagnosed with KLS, a person must meet first the criteria for recurrent hypersomnia: Episodes of excessive sleepiness lasting between two days and five weeks. Episodes occur at least once every 18 months and often more frequently. Normal behavior and cognition between episodes.
Which of the following symptoms is associated with Kleine Levin Syndrome also known as Sleeping Beauty Disorder )?
KleineLevin syndrome (KLS), also called Sleeping beauty syndrome is a rare, disorder predominantly reported in adolescent males, characterized by recurrent episodes of hypersomnia and to various degrees, hyperphagia, cognitive disturbances, and hypersexuality.
What is EDS sleep disorder?
Many sleep disorders manifest with insomnia and usually excessive daytime sleepiness (EDS). Insomnia is difficulty falling or staying asleep, early awakening, or a sensation of unrefreshing sleep. EDS is the tendency to fall asleep during normal waking hours.
Is there a cure for FFI?
There is no cure for FFI. Treatment is directed toward management of the specific symptoms that are apparent in each individual.
How do you know if you have sleeping beauty syndrome?
Sleeping Beauty Syndrome Signs and Symptoms Abrupt onset, sometimes accompanied by flu-like symptoms. Spaciness or childishness. Lethargy. Excessive food intake or food cravings while awake.
What do you do for hypersomnia?
Such as:
- Try to maintain a regular sleeping schedule.
- Sleep in a peaceful room.
- Do not stay awake until late at night.
- Limit alcohol intake (less than 2 drinks/day for men and less than 1 drink/day for women)
- Do not take caffeine 4-5 hours before going to bed at night.
Why do I hump in my sleep?
Causes of Sleep Sex When you fall asleep in close proximity to someone, being jostled or bumped can trigger a desire for sex that you act on, though you’re asleep, Mangan says. Some researchers cite drugs and alcohol as a cause of sexsomnia. Fatigue and stress also are considered likely causes.
What do you call a person who talks in their sleep?
Sleep talking, formally known as somniloquy, is a sleep disorder defined as talking during sleep without being aware of it. Sleep talking can involve complicated dialogues or monologues, complete gibberish or mumbling.
What is the exploding head syndrome?
Exploding head syndrome (EHS) is an under-recognized parasomnia characterized by a complaint of sudden loud noise or a sense of explosion in the head that usually occurs at sleep onset.
How do you get rid of exploding head syndrome?
Clomipramine, an antidepressant, is a common treatment for exploding head syndrome. Calcium channel blockers may also help. See your doctor if you think you need medicine for it.
What illness makes you sleep for days?
Narcolepsy is a chronic sleep disorder characterized by overwhelming daytime drowsiness and sudden attacks of sleep. People with narcolepsy often find it difficult to stay awake for long periods of time, regardless of the circumstances. Narcolepsy can cause serious disruptions in your daily routine.
Is there something similar to sleep paralysis?
Sleep paralysis is similar to cataplexy in that it represents a paralysis of muscle activity that normally only occurs during REM sleep. Sleep paralysis occurs on the edges of sleep, but cataplexy occurs after a person is fully awake.
What are three common sleep problems in early childhood?
The most common sleep problems in young children are:
- Problems Getting to Sleep: Getting your child to settle down at bedtime can seem impossible sometimes. …
- Not Being Able to Get Back to Sleep: Most of us wake up a few times in the night, but we just drift back to sleep without being aware of it. …
- Nightmares:
How do I help my child sleep?
How to sleep better for children: tips
- Set up a bedtime routine. …
- Relax before bedtime. …
- Keep regular sleep and wake times. …
- Keep older children’s naps early and short. …
- Make sure your child feels safe at night. …
- Check noise and light in your child’s bedroom. …
- Avoid the clock. …
- Eat the right amount at the right time.
What causes not to sleep at night?
Insomnia, the inability to get to sleep or sleep well at night, can be caused by stress, jet lag, a health condition, the medications you take, or even the amount of coffee you drink. Insomnia can also be caused by other sleep disorders or mood disorders such as anxiety and depression.